Coffee may worsen Alzheimer’s symptoms

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Washington, April 5 (TNS): At Medical News Today, we often report on studies yielding the health benefits of drinking coffee. New research, however, now suggests that our beloved cup of joe might have a darker side, after finding that long-term caffeine intake could exacerbate symptoms of Alzheimer’s disease.

Researchers suggest that long-term caffeine consumption may worsen the behavioural symptoms of Alzheimer’s. In a study of mice with Alzheimer’s, researchers found that prolonged exposure to caffeine was linked to increases in behavioural symptoms of the disease, such as anxiety. Around 5.7 million adults in the United States live with Alzheimer’s disease, and every 65 seconds, one more person in the country develops the condition.

The most widely recognized symptom of Alzheimer’s is memory loss, but the disease can present a number of other symptoms, including delusions, hallucinations, irritability, anxiety, and depression.
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Dr. Giménez-Llort and her team refer to these as the behavioural and psychological symptoms of dementia (BPSD).

Previous research has suggested that coffee has the potential to lower the risk of Alzheimer’s and other dementias. For individuals who already have Alzheimer’s, however, the effects of caffeine consumption may not be so beneficial, according to Dr. Giménez-Llort and her team. The researchers came to their conclusion by studying the effects of caffeine on mouse models of Alzheimer’s disease. The mice develop Alzheimer’s disease in a very close manner to the human patients with an early-onset form of the disease,” explains first author Raquel Baeta-Corral, also of the Universitat Autònoma de Barcelona.